General Cell Based Assays
Eurofins Discoverx PathHunter eXpress SSTR1 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0307E3CP5M)
The PathHunter SSTR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin) based activation of SSTR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR1 and EA-tagged β-Arrestin-2. Activation of SSTR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human CD28 Signaling Cell-Based Assay Kit (Jurkat)
The PathHunter Human CD28 (GRB2) Signaling Stable Cell Line Assay (Jurkat) measures CD28 signal by recruitment of SH2 domain protein to the activated receptor. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Meso Scale Discovery U-PLEX Mouse IL-33 ASY
The Meso Scale Discovery U-PLEX Mouse IL-33 Assay Kit is a multiplex immunoassay for detecting and quantifying mouse interleukin 33 (IL-33) in serum plasma and cell culture supernatants It uses MSD s electrochemiluminescent detection technology offering high sensitivity a wide dynamic range and low sample volume needs The kit includes a 96-well plate with capture antibodies detection antibodies calibrator diluent wash buffer read buffer and a 10-point standard curve The assay takes about 3 5 hours and is compatible with lab automation systems enhancing biomarker research efficiency
Eurofins Discoverx cAMP Hunter™ Human ADRA2A Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human ADRA2A Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure ADRA2A (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse HTR2C (5-HT2C) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Mouse HTR2C (5-HT2C) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure mHTR2C (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse CTLA4 Signaling Cell-Based Assay Kit (Jurkat)
The PathHunter Mouse CTLA4 (SHP1) Signaling Stable Cell Line Assay (Jurkat) measures CTLA4 signal by recruitment of SH2 domain protein to the activated receptor. Please note this product expresses the mouse version of CTLA-4. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx SPRINTer™ Human BRD4 Targeted Protein Degradation Cell-Based Assay Kit (K562)
The SPRINTer™ Human BRD4 Targeted Protein Degradation Stable Cell Line Assay (K562) contains a stable clonal cell line used for monitoring drug-induced protein turnover of BRD4, supporting TPD studies. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress ADRB2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0182E2CP0M)
The PathHunter ADRB2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. isoproterenol) based activation of ADRB2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged ADRB2 and EA-tagged β-Arrestin-2. Activation of ADRB2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human SSTR2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human SSTR2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure SSTR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Meso Scale Discovery R-PLEX Rat KC/GRO ASY
The R-PLEX Rat KC/GRO Assay from Meso Scale Diagnostics is a multiplex immunoassay kit for measuring rat keratinocyte chemoattractant (KC) and growth-regulated oncogene (GRO) in various samples It uses electrochemiluminescence (ECL) and MSD s MULTI-ARRAY technology offering high sensitivity and a wide dynamic range The kit includes a 96-well plate with specific capture antibodies detection antibodies and calibrators Results are read on MSD platforms and analyzed with MSD Discovery Workbench software enabling efficient analysis of these neutrophil chemoattractants
Eurofins Discoverx PathHunter Human PR beta Nuclear Receptor Protein Interaction Cell-Based Assay Kit (U2OS)
The PathHunter Human PR beta Nuclear Receptor Stable Cell Line Protein Interaction Assay (U2OS) contains a stable clonal cell line used to measure activated PRβ nuclear hormone receptor interaction with SRCPs. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human MIP-3α (CCR6) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MIP-3α (CCR6) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCR6 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR157 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR157 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR157 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR37L1 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR37L1 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR37L1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
LGC GENOMICS LLC sbeade pathogen nucleic acid purification kit (96 purifications)
Key features:Rapid nucleic acid purification from various pathogensIncludes Proteinase K to facilitate efficient cell disruption and nucleic acid releaseHigh-quality sbeadex magnetic bead-based technologyReady-to-use kit compatible with most robotic platformsSuitable for most downstream applications such as: PCR/qPCR, RT-PCR/qRT-PCR, and NGS